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Brand:whmoli
Description:Basic Info Product name:Raloxifene hydrochloride Synonyms:Keoxifene CAS No.:82640-04-8 M.F.:C28H29NO4S M.W.:475.5992 Appearance:light yellow crystalline powder USES:Raloxifene will be like tamoxifen as effective,and less adverse effects
Origin:China Hubei
Model:82640-04-8
MOQ:10GramsGram/Grams
Port:Hong Kong,Shanghai,Shenzhen
Payment Terms:T/T
Supply Time:Day
Delivery Time:2017-09-13
Packaging Details:Suitable package according to your quantity
Product detail:
Basic Info
Raloxifene hydrochloride Descript ion:
Raloxifene hydrochloride is a second-generation Selective Estrogen Receptor Modulator (SERM) of the benzothiophene family.This drug is similar in effect to tamoxifen, exhibiting estrogen receptor antagonist (blocking) properties in some tissues while acting as an estrogen receptor agonist (activator) in others.
The main point of variation between these two agents is their tissue selectivity.While raloxifene hydrochloride is a strong anti-estrogen in breast and uterine tissues,it appears to be estrogenic in bone.This allows it to protect bone density,mimicking the beneficial effects of endogenous estradiol.This is quite different from tamoxifen,which is anti-estrogenic in both breast and bone.
In a role that was novel for an anti-estrogen,raloxifene hydrochloride was approved by the FDA for the prevention and treatment of osteoporosis in post-menopausal women.It is also being investigated for several other potential uses,including the treatment and prevention of cardiovascular disease,breast cancer,gynecomastia, prostate cancer,acromegaly,and uterine cancer.
Usage:
Evista is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women,the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer.Evista is supplied as a 60 mg tablet designed for oral administration.The recommended initial dose of the drug is one 60 mg tablet daily,which may be administered any time of day without regard to meals.
Application:
Raloxifene Hydrochlorid is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women,the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer.Raloxifene Hydrochlorid is supplied as a 60 mg tablet designed for oral administration.The recommended initial dose of the drug is one 60 mg tablet daily,which may be administered any time of day without regard to meals.
Raloxifene hydrochloride Mechanism of Action:
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist,referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds.The biological actions of raloxifene are largely mediated through binding to estrogen receptors.
This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism).The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors.
appears to act as an estrogen agonist in bone.It decreases bone resorption and bone turnover, increases bone mineral density and decreases fracture incidence.
Company profile:
We are Wuhan Magic Biotechnology Co., Ltd. and our main products include:pharmaceutical intermediates,injectable anabolic steroids,health care products,sarms,antibiotics,,cardiovascular drugs,cephalosporin products,bile acid products,weight loss drugs and so on.Which is widely used in bodybuilding,medicine,food&beverage,health care and other industries.We have much experiences in the field for many years.We can give you the products in very competitive price with higher quality.
Why Choose us?
1.Rich experience.We are a professional trading company in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
2.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.
3.Safe and fast delivery.
4.Good after-sales service.
a).We will ship the goods within 5days after get your payments.If you want to cancel or change order,please tell me within 24hours after you finish the payment.So we both can make the best of the bad bargain.
b).We will ship the goods that you order from us by EMS,HKEMS,DHL,UPS,or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
c).If the goods were lost or not received for other reasons,please contact me Immediately.
Welcome to inquiry!
If you have any problems or you want to know more informations,please contact us anytime.We will always be at your service!
| Product name | Raloxifene hydrochloride |
| Synonyms | Keoxifene |
| CAS No. | 82640-04-8 |
| M.F. | C28H29NO4S |
| M.W. | 475.5992 |
| Appearance | light yellow crystalline powder |
Raloxifene hydrochloride De
Raloxifene hydrochloride is a second-generation Selective Estrogen Receptor Modulator (SERM) of the benzothiophene family.This drug is similar in effect to tamoxifen, exhibiting estrogen receptor antagonist (blocking) properties in some tissues while acting as an estrogen receptor agonist (activator) in others.
The main point of variation between these two agents is their tissue selectivity.While raloxifene hydrochloride is a strong anti-estrogen in breast and uterine tissues,it appears to be estrogenic in bone.This allows it to protect bone density,mimicking the beneficial effects of endogenous estradiol.This is quite different from tamoxifen,which is anti-estrogenic in both breast and bone.
In a role that was novel for an anti-estrogen,raloxifene hydrochloride was approved by the FDA for the prevention and treatment of osteoporosis in post-menopausal women.It is also being investigated for several other potential uses,including the treatment and prevention of cardiovascular disease,breast cancer,gynecomastia, prostate cancer,acromegaly,and uterine cancer.
Usage:
Evista is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women,the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer.Evista is supplied as a 60 mg tablet designed for oral administration.The recommended initial dose of the drug is one 60 mg tablet daily,which may be administered any time of day without regard to meals.
Application:
Raloxifene Hydrochlorid is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women,the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer.Raloxifene Hydrochlorid is supplied as a 60 mg tablet designed for oral administration.The recommended initial dose of the drug is one 60 mg tablet daily,which may be administered any time of day without regard to meals.
Raloxifene hydrochloride Mechanism of Action:
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist,referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds.The biological actions of raloxifene are largely mediated through binding to estrogen receptors.
This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism).The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors.
appears to act as an estrogen agonist in bone.It decreases bone resorption and bone turnover, increases bone mineral density and decreases fracture incidence.
Company profile:
We are Wuhan Magic Biotechnology Co., Ltd. and our main products include:pharmaceutical intermediates,injectable anabolic steroids,health care products,sarms,antibiotics,,cardiovascular drugs,cephalosporin products,bile acid products,weight loss drugs and so on.Which is widely used in bodybuilding,medicine,food&beverage,health care and other industries.We have much experiences in the field for many years.We can give you the products in very competitive price with higher quality.
Why Choose us?
1.Rich experience.We are a professional trading company in China for many years,our products have exported to Germany,Spain,UK,USA,Australia,Middle East and so many other countries,and we have got very good feedback from our customers,we had Established many long friendly relations of cooperation.
2.Great quality,purity and competitive price.Different country with different and suitable way of packing.Packing pictures will be sent to you as soon as possible after your payment.
3.Safe and fast delivery.
4.Good after-sales service.
a).We will ship the goods within 5days after get your payments.If you want to cancel or change order,please tell me within 24hours after you finish the payment.So we both can make the best of the bad bargain.
b).We will ship the goods that you order from us by EMS,HKEMS,DHL,UPS,or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
c).If the goods were lost or not received for other reasons,please contact me Immediately.
Welcome to inquiry!
If you have any problems or you want to know more informations,please contact us anytime.We will always be at your service!
