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Qingdao Fraken International Trading Co., Ltd.
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Paliperidone
Cas No:144598-75-4
MF:C23H27FN4O3
Use:atypical antipsychotic
Appearance:white crystalline powder
Paliperidone
1.General info:Paliperidone also known as 9-hydroxyrisperidone, is an atypical antipsychotic, it is an extended release formulation of paliperidone that uses the OROS extended release system to allow for once-daily dosing. paliperidone palmitate is a long-acting injectable formulation of paliperidone indicated for once-monthly injection after an initial titration period. Chemically, paliperidone is the primary active metabolite of the older atypical antipsychotic risperidone (paliperidone is 9-hydroxyrisperidone, i.e. risperidone with an extra hydroxyl group). It is indicated for the acute and maintenance treatment of schizophrenia.
2. Pharmacology: While its specific mechanism of action is unknown, it is believed paliperidone and risperidone act via similar, if not identical, pathways; therapeutic effect may be due to a combination of D2 and 5-HT2A receptor antagonism. Paliperidone also has antagonist effect at α1 and α2 adrenergic receptors and at H1 histamine receptors. It does not bind to muscarinic acetylcholine receptors.
Paliperidone was approved by the FDA for the treatment of schizophrenia on December 20, 2006. This agent will initially be marketed for the treatment of schizophrenia and then for bipolar mania. Clinical trials of paliperidone for the treatment of schizoaffective disorder are also planned. It may also be used off-label for other conditions. Like risperidone, its possible use in people with autism and Asperger syndrome may be studied.
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Good day, my dear friend. Welcome to our website and we’ll be very glade also thankful to receive your Inquiry and advice.
Just have a try to visit our website for seconds and we must give you a big surprise
Ourselves
1).10 years experience in plant extract
2). HACCP and KOSHER certificated
3). GMP factory
4). Large quantity in stock
Product characteristics
1). extracted from the natural Onion with a special process, the whole process
Conforms to the GMP requirements strictly
2). we have gained ISO, HACCP, KOSHER, AND GMP certificate
3). water and ethanol as solvent, ensure the safety of the product
4). complete product tracing system and technical service
SECOND------ Our main products
1.Stevia extract | RA97% |
2.Pomegranate extract | ellagic acid 90% |
3.Onion extract powder | 10:1 |
4.Wolfberry extract | polysaccharide 50% |
5.Olive leaf extract | 30% HPLC |
6.Epimedium extract | icariin 10-90% |
7.Amur cork-tree extract |
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8.Dodder seed extract | 60% |
9.Lemon balm extract | flavone 3-5% |
10.Coix seed extract | GMP factory |
11.Platycodon root extract |
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12.Hawthorn extract | GMP factory |
13.Angelica extract |
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14.Smoketree extract |
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15.Horse chestnut extract | 10-98% |
16.Senna lesf extract |
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17.Polygonum extract | 10:1 |
18.Banaba leaf extract | 1-10% |
19.Shiitake mushroom extract | polysaccharide 20% |
20.Reishi extract | polysaccharide 30% |
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To get more information, just feel free to contact with us. Thanks.
Mr. Liu
Qingdao fraken international trading co., ltd
Address: RM1005 post mansion yan’an three road ,qingdao ,China
Tel: 0086 532 83899718
Fax: 0086 532 83623236
Web: http://fraken.en.alibaba.com