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| Product Name | L-Thyroxine |
| Other Name | T4 |
| Purity | 98%min |
| CAS No. | 51-48-9 |
| M.W. | 776.87 |
| M.F. | C15H11I4NO4 |
| Assay | HPLC |
| Melting Point | 223ºC |
| Water Solubility | Insoluble |
| Appearance | White powder |
De
L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4),which is naturally secreted by the follicular cells of the thyroid gland.It is used to treat thyroid hormone deficiency,and occasionally to prevent the recurrence of thyroid cancer.Like its naturally secreted counterpart,levothyroxine is achiral compound in the L-form.The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated cholesterol levels) but was withdrawn due to cardiac side effects.It is on the World Health Organization's List of Essential Medicines,a list of the most
Application:
L-thyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism,who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH),a hormone that is considered goiter-inducing.L-thyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
Levothyroxine (T4) is a synthetically prepared levo isomer of thyroxine,the major hormone secreted from the thyroid gland.Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood.Thyroxine is peripherally deiodinated to form triiodothyronine (T3) which exerts a broad spectrum of stimulatory effects on cell
Thyroid hormone increases the
In adults,thyroid hormone helps to maintain brain function, food
COA
| Product name | L-Thyroxine | |
| Appearance | White crystalline powder | |
| Assay(*) | 98~101.0% | 99.3% |
| Identification | By UV, To match with working standard | Complies |
| Related Substances | Not more than the reference solution (0.05%) | Complies |
| Heavy |
≤10ppm | 10ppm |
| Loss on drying | <0.5% | 0.15% |
| Resiue on ignition | ≤0.1% | 0.05% |
| Melting | 235°C | Complies |
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