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Basic Info
Usage:
This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause.Femara is also used to help prevent the cancer from returning.Some breast cancers are made to grow faster by a natural hormone called estrogen.Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
Other USES:
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional.Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This medication may also be used to treat infertility in women.
Application:
Femara is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women.It is often given to women who have been taking tamoxifen Nolvadex,Soltamox) for 5 years.Femara is available in generic form.Common side effects of Femara include hot flashes,hair loss,joint/bone/muscle pain,tiredness,unusual sweating or night sweats,nausea,diarrhea,dizziness,trouble sleeping,drowsiness,weight gain,weakness,flushing (warmth,redness,or tingly feeling),headache,constipation,numbness/tingling/weakness/stiffness in your hand or fingers,or pain in your hand that spreads to your arm,wrist,forearm or shoulder.
Brief Descript ion:
Femara is a type of hormone therapy drug used to treat breast cancer in women who have had their menopause.It is also called Femara.
How Femara works
Femara lowers the levels of the female sex hormone oestrogen in the body.Oestrogen stimulates some breast cancers to grow.These breast cancers are called hormone sensitive or hormone receptor positive.Femara can stop or slow the growth of these cancers.It can also reduce the chance of a breast cancer coming back after surgery.
Femara only works in women who have had their menopause.It is a type of drug called an aromatase inhibitor.After the menopause,women don't produce oestrogen from their ovaries.But they still produce a small amount by using an enzyme called aromatase which turns other sex hormones called androgens into oestrogen.This change happens mainly in fatty tissue,muscle and the skin.Aromatase inhibitors block aromatase so that it can't change the androgen into oestrogen.
COA
Other Anti-Estrogens&PCT Powders
Tamoxifen Citrate CAS 54965-24-1
Raloxifene Hydrochloride CAS 82640-04-8
Clomifene citrate(Clomid) CAS 50-41-9
M-esterolone(Proviron) CAS 1424-00-6
L-etrozole(Femara) CAS 112809-51-5
A-nastrozole(Arimidex) CAS 120511-73-1
E-xemestane(Aromasin) CAS 107868-30-4
F-ormestane(Lentaron) CAS 566-48-3
Toremifene Citrate CAS 89778-27-8
Finasteride(Proscar,Propecia) CAS 98319-26-7
Dutasteride(Avodart) CAS 164656-23-9
T-estolactone(Teslac) CAS 968-93-4
| Product Name | L-etrozole |
| Synonyms | Femara;Letrozol |
| CAS No. | 112809-51-5 |
| M.F. | C17H11N5 |
| M.W. | 285.3 |
| Assay | 99% |
| Appearance | White or white crystalline powder |
Usage:
This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause.Femara is also used to help prevent the cancer from returning.Some breast cancers are made to grow faster by a natural hormone called estrogen.Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
Other USES:
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional.Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This medication may also be used to treat infertility in women.
Application:
Femara is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women.It is often given to women who have been taking tamoxifen Nolvadex,Soltamox) for 5 years.Femara is available in generic form.Common side effects of Femara include hot flashes,hair loss,joint/bone/muscle pain,tiredness,unusual sweating or night sweats,nausea,diarrhea,dizziness,trouble sleeping,drowsiness,weight gain,weakness,flushing (warmth,redness,or tingly feeling),headache,constipation,numbness/tingling/weakness/stiffness in your hand or fingers,or pain in your hand that spreads to your arm,wrist,forearm or shoulder.
Brief De
Femara is a type of hormone therapy drug used to treat breast cancer in women who have had their menopause.It is also called Femara.
How Femara works
Femara lowers the levels of the female sex hormone oestrogen in the body.Oestrogen stimulates some breast cancers to grow.These breast cancers are called hormone sensitive or hormone receptor positive.Femara can stop or slow the growth of these cancers.It can also reduce the chance of a breast cancer coming back after surgery.
Femara only works in women who have had their menopause.It is a type of drug called an aromatase inhibitor.After the menopause,women don't produce oestrogen from their ovaries.But they still produce a small amount by using an enzyme called aromatase which turns other sex hormones called androgens into oestrogen.This change happens mainly in fatty tissue,muscle and the skin.Aromatase inhibitors block aromatase so that it can't change the androgen into oestrogen.
COA
| Tests | Specifications | Results |
| Appearance | White or off-white crystaline powder | White Crystalline powder |
| Solubility | Soluble in Chloroform; Soluble in ethanol when heated |
Conform |
| ldentification | (1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm |
Conform Conform |
| (2)Infrared spectrum should be in accordance the dominant peak of contrast | In accordance with the dominant peak of contrast | |
| Melting points | 182ºC-184ºC | 182ºC |
| Related substances | ≤0.5% | 0.3% |
| Single impurity | ≤0.3% | 0.2% |
| Loss on drying | ≤1.0% | 0.8% |
| [Assay]C17H11N5 (On anhydrous basis) |
≥98.0% | 99.2% |
| Conclusion | Conforms Specifications of Enterprise Standard. | |
Other Anti-Estrogens&PCT Powders
Tamoxifen Citrate CAS 54965-24-1
Raloxifene Hydrochloride CAS 82640-04-8
Clomifene citrate(Clomid) CAS 50-41-9
M-esterolone(Proviron) CAS 1424-00-6
L-etrozole(Femara) CAS 112809-51-5
A-nastrozole(Arimidex) CAS 120511-73-1
E-xemestane(Aromasin) CAS 107868-30-4
F-ormestane(Lentaron) CAS 566-48-3
Toremifene Citrate CAS 89778-27-8
Finasteride(Proscar,Propecia) CAS 98319-26-7
Dutasteride(Avodart) CAS 164656-23-9
T-estolactone(Teslac) CAS 968-93-4
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